Flow control among microvessels coordinated by intercellular conduction.

  title={Flow control among microvessels coordinated by intercellular conduction.},
  author={Steven S Segal and Brian R. Duling},
  volume={234 4778},
Optimal distribution of blood flow requires coordination of vasodilation among resistance vessels. During hyperemia, blood vessels dilate upstream from the initiating stimulus. Spreading vasodilation independent of flow changes has not been previously demonstrated. In the present study, iontophoresis of acetylcholine adjacent to single hamster cheek pouch arterioles in situ (diameter, 20 to 37 micrometers) induced a rapid bidirectional dilation that was not attenuated when blood flow was… CONTINUE READING
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