Flow-based microimmunoassay.

@article{Hayes2001FlowbasedM,
  title={Flow-based microimmunoassay.},
  author={Mark A. Hayes and T N Polson and Allison N. Phayre and Antonio A. Garcia},
  journal={Analytical chemistry},
  year={2001},
  volume={73 24},
  pages={
          5896-902
        }
}
A small-volume heterogeneous immunoassay system is demonstrated in microchannels exploiting magnetic manipulations of small paramagnetic particles (1-2-microm diameter). The small-diameter particles help to create a high surface-area-to-volume ratio that generates the sensitivity for the small detection volumes. Flow characteristics of the magnetically formed packed bed within the channel allow the assay to be carried out quickly (minutes) while passing appropriate volumes of both samples and… CONTINUE READING

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