Flotillin-1 promotes tumor necrosis factor-α receptor signaling and activation of NF-κB in esophageal squamous cell carcinoma cells.


BACKGROUND & AIMS The flotillin family of proteins, including flotillin-1 (FLOT1 or Reggie-2), are lipid raft proteins that initiate receptor kinase signaling and are up-regulated in several tumor types. We investigated the role of FLOT1 signaling and activation of the transcription factor nuclear factor (NF)-κB in esophageal squamous cell carcinoma (ESCC… (More)
DOI: 10.1053/j.gastro.2012.06.033


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.


Citations per Year

260 Citations

Semantic Scholar estimates that this publication has 260 citations based on the available data.

See our FAQ for additional information.

Slides referencing similar topics