Flot-2 Expression Correlates with EGFR Levels and Poor Prognosis in Surgically Resected Non-Small Cell Lung Cancer

@inproceedings{Wen2015Flot2EC,
  title={Flot-2 Expression Correlates with EGFR Levels and Poor Prognosis in Surgically Resected Non-Small Cell Lung Cancer},
  author={Qiuyuan Wen and Weiyuan Wang and Shuzhou Chu and Jiadi Luo and Lingjiao Chen and Guiyuan Xie and Lina Xu and Meirong Li and Songqing Fan and Yves St-Pierre},
  booktitle={PloS one},
  year={2015}
}
We previously reported that expression of Flotillin 2 (Flot-2), a protein isolated from caveolae/lipid raft domains, increased significantly in nasopharyngeal carcinoma (NPC) compared with normal tissues. Signal transduction through epidermal growth factor receptors (EGFR) and Flot-2 play an important role in cancer development, but their precise role in lung cancer has not been investigated. In this study, we have investigated the correlation between the expression of Flot-2 and EGFR, which… CONTINUE READING