Flexible sigmoidoscopy in the randomized prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial: added yield from a second screening examination.

@article{Weissfeld2012FlexibleSI,
  title={Flexible sigmoidoscopy in the randomized prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial: added yield from a second screening examination.},
  author={Joel L. Weissfeld and Robert E. Schoen and Paul F. Pinsky and Robert S. Bresalier and Vincent Paul Doria-Rose and Adeyinka O Laiyemo and Timothy Church and Lance A Yokochi and Susan Yurgalevitch and Joshua M. Rathmell and Gerald L. Andriole and Saundra S. Buys and E. David Crawford and Mona Fouad and Claudine Isaacs and Lois E. Lamerato and Douglas Reding and Philip C Prorok and C. T. van den Berg},
  journal={Journal of the National Cancer Institute},
  year={2012},
  volume={104 4},
  pages={280-9}
}
BACKGROUND Among randomized trials evaluating flexible sigmoidoscopy (FSG) for its effect on colorectal cancer mortality, only the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial screened its participants more than one time. We report outcomes from the PLCO screening FSG program and evaluate the increased yield produced by a second FSG. METHODS Participants were screened by 60-cm FSG in 10 regional screening centers at study entry and 3 or 5 years later, depending on the… CONTINUE READING
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