Flexible sequence similarity searching with the FASTA3 program package.

@article{Pearson2000FlexibleSS,
  title={Flexible sequence similarity searching with the FASTA3 program package.},
  author={W. Pearson},
  journal={Methods in molecular biology},
  year={2000},
  volume={132},
  pages={
          185-219
        }
}
  • W. Pearson
  • Published 2000
  • Computer Science, Medicine
  • Methods in molecular biology
  • The FASTA3 and FASTA2 packages provide a flexible set of sequence-comparison programs that are particularly valuable because of their accurate statistical estimates and high-quality alignments. Traditionally, sequence similarity searches have sought to ask one question: "Is my query sequence homologous to anything in the database?" Both FASTA and BLAST can provide reliable answers to this question with their statistical estimates; if the expectation value E is < 0.001-0.01 and you are not doing… CONTINUE READING
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