Flexible and Accurate Detection of Genomic Copy-Number Changes from aCGH

@article{Rueda2007FlexibleAA,
  title={Flexible and Accurate Detection of Genomic Copy-Number Changes from aCGH},
  author={Oscar M. Rueda and Ram{\'o}n D{\'i}az-Uriarte},
  journal={PLoS Computational Biology},
  year={2007},
  volume={3},
  pages={S11 - S17}
}
Genomic DNA copy-number alterations (CNAs) are associated with complex diseases, including cancer: CNAs are indeed related to tumoral grade, metastasis, and patient survival. CNAs discovered from array-based comparative genomic hybridization (aCGH) data have been instrumental in identifying disease-related genes and potential therapeutic targets. To be immediately useful in both clinical and basic research scenarios, aCGH data analysis requires accurate methods that do not impose unrealistic… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 73 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

73 Citations

01020'09'12'15'18
Citations per Year
Semantic Scholar estimates that this publication has 73 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 52 references

Inference in hidden Markov models (Springer series in statistics)

  • O Cappé, E Moulines, T Ryden
  • New York: Springer
  • 2005
Highly Influential
19 Excerpts

Modeling of multivariate time series using hidden Markov models [dissertation

  • S Kirshner
  • Irvine (California): University of California…
  • 2005
Highly Influential
17 Excerpts

Similar Papers

Loading similar papers…