Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization.

@article{Kolawole2014FlexibilityIS,
  title={Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization.},
  author={Abimbola Olayinka Kolawole and Ming Li and Chunsheng Xia and Audrey E. Fischer and Nicholas Scott Giacobbi and Christine M. Rippinger and Jody B. G. Proescher and Susan K. Wu and Seneca L. Bessling and Monica Gamez and Chenchen Yu and Rebecca V. Zhang and T. Mehoke and James M. Pipas and Joshua T. Wolfe and Jeffrey Lin and Andrew B. Feldman and Thomas James Smith and Christiane E Wobus},
  journal={Journal of virology},
  year={2014},
  volume={88 8},
  pages={4543-57}
}
UNLABELLED New human norovirus strains emerge every 2 to 3 years, partly due to mutations in the viral capsid that allow escape from antibody neutralization and herd immunity. To understand how noroviruses evolve antibody resistance, we investigated the structural basis for the escape of murine norovirus (MNV) from antibody neutralization. To identify… CONTINUE READING