Flecainide-induced aggravation of ventricular tachycardia.

  title={Flecainide-induced aggravation of ventricular tachycardia.},
  author={Stefan H. Hohnloser and Andreas Michael Zeiher and Martin H Hust and Helmut Wollschl{\"a}ger and Hanjorg Just},
  journal={Clinical cardiology},
  volume={6 3},
Flecainide acetate is a new class I antiarrhythmic agent which slows atrial, A-V nodal and ventricular conduction velocity, and prolongs refractoriness of these structures (Borchard et al., 1982; Hodess et al., 1979). Recent studies with oral flecainide therapy suggested its high potential for suppression of ventricular tachycardia in humans (Anderson et al., 1981; Duff et al., 1981; Hodges et al., 1982). Its favorable pharmacokinetics with an average plasma half-time of about 20 hours allows… CONTINUE READING

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