Flecainide-associated pneumonitis with acute respiratory failure in a patient with the LEOPARD syndrome
@article{Robain2000FlecainideassociatedPW, title={Flecainide-associated pneumonitis with acute respiratory failure in a patient with the LEOPARD syndrome}, author={Anne Robain and H Perchet and Claire Fchrman}, journal={Acta Cardiologica}, year={2000}, volume={55}, pages={45 - 47} }
Antiarrhythmic agents can cause pneumonitis. Flecainide is a rare cause of hypersensitivity pneumonitis, and few cases have been reported. We describe a case of interstitial hypoxaemiant pneumonitis probably related to flecainide in a patient with the LEOPARD syndrome, a rare congenital disorder.
5 Citations
Diffuse Infiltrative Lung Disease Associated with Flecainide
- MedicineRespiration
- 2002
Two patients who developed subacute diffuse infiltrative lung disease while receiving flecainide for supraventricular arrhythmia were presented and increased numbers of lymphocytes and eosinophils, and a low CD4/CD8 ratio were revealed.
Flecainide-induced pneumonitis: a case report
- MedicineJournal of Medical Case Reports
- 2022
Clinical and radiological improvement was noted after corticosteroid therapy, but the patient died from septic complications, and flecainide-induced lung injury has rarely been reported in the literature and remains a diagnosis of exclusion.
Anaesthetic implications of LEOPARD syndrome
- MedicinePaediatric anaesthesia
- 2004
The authors present a 4‐year old boy who presented for anaesthetic care for repair of a ventricular septal defect and pulmonary valvotomy for congenital pulmonary stenosis and the potential perioperative implications of LEOPARD syndrome are discussed.
Drug-induced and iatrogenic respiratory disease
- Medicine, BiologyERS Handbook Respiratory Medicine
- 2019
Pneumonitis induced by non-cytotoxic agents Amiodarone pulmonary toxicity Eosinophilic pneumoniainduced by drugs Bronchiolitis obliterans organizing pneumonia induced by drugs or radiotherapy.
References
SHOWING 1-10 OF 10 REFERENCES
Tocainide-associated interstitial pneumonitis.
- MedicineThorax
- 1982
It appears that in patients with life-threatening ventricular arrhythmias, tocainide is a safe agent with a favourable risk-benefit ratio.
Multiple lentigines syndrome. Case report and review of the literature.
- MedicineThe American journal of medicine
- 1976
Irreversible interstitial pneumonitis associated with tocainide therapy.
- Medicine, BiologyThe Western journal of medicine
- 1988
32. Graettinger JS, Muenster JJ, Selvertone LA, et al: A correlation of clinical and hemodynamic studies in patients with hyperthyroidism with and without congestive heart failure. J Clin Invest…
Lazarus 'vi . L1 C lrrevcr~1hlc 1111er~ti tial pncumonit1s associa1ed with tocainide Lherap)
- We.it J .\led
- 1988
associated , 1th cutaneous lenllg111os1s. allom:d d1agno-;1.., of the LEOP.\RD s)-ndrome. S1.\ month-. later the patient reports
- PO:! T 1 mm Hg. PCO 2 36 mm Hg
Mulllple lentigine, syndrome. Case repon ant.I re\1c,~ of literature
Tocm n1dc: 101crsulial pneumomus
- J Am ( ol/ Ccmliol