Flecainide-associated pneumonitis with acute respiratory failure in a patient with the LEOPARD syndrome

  title={Flecainide-associated pneumonitis with acute respiratory failure in a patient with the LEOPARD syndrome},
  author={Anne Robain and H Perchet and Claire Fchrman},
  journal={Acta Cardiologica},
  pages={45 - 47}
Antiarrhythmic agents can cause pneumonitis. Flecainide is a rare cause of hypersensitivity pneumonitis, and few cases have been reported. We describe a case of interstitial hypoxaemiant pneumonitis probably related to flecainide in a patient with the LEOPARD syndrome, a rare congenital disorder. 
5 Citations

Diffuse Infiltrative Lung Disease Associated with Flecainide

Two patients who developed subacute diffuse infiltrative lung disease while receiving flecainide for supraventricular arrhythmia were presented and increased numbers of lymphocytes and eosinophils, and a low CD4/CD8 ratio were revealed.

Flecainide-induced pneumonitis: a case report

Clinical and radiological improvement was noted after corticosteroid therapy, but the patient died from septic complications, and flecainide-induced lung injury has rarely been reported in the literature and remains a diagnosis of exclusion.

Anaesthetic implications of LEOPARD syndrome

The authors present a 4‐year old boy who presented for anaesthetic care for repair of a ventricular septal defect and pulmonary valvotomy for congenital pulmonary stenosis and the potential perioperative implications of LEOPARD syndrome are discussed.

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Pneumonitis induced by non-cytotoxic agents Amiodarone pulmonary toxicity Eosinophilic pneumoniainduced by drugs Bronchiolitis obliterans organizing pneumonia induced by drugs or radiotherapy.



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