Flavonolignans Inhibit IL1-β-Induced Cross-Talk between Blood Platelets and Leukocytes


Interleukin-1 beta (IL-1β)-the most potent pro-inflammatory is responsible for a broad spectrum of immune and inflammatory responses, it induces T-cell and B-cell activation and consequently the synthesis of other pro-inflammatory cytokines (such as IFN-γ and TNF). IL-1β induces the formation of blood platelet-leukocyte aggregates (PLAs), which suggests… (More)
DOI: 10.3390/nu9091022


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