Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death.

@article{Zhu2007FlavonoidsPN,
  title={Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death.},
  author={Judy Ting Ting Zhu and Roy Chi Yan Choi and Glanice Kin-Yan Chu and Anna Wing-han Cheung and Qiu T. Gao and Jun Li and Zhi Ye Jiang and Tina Ting-xia Dong and Karl Wah-Keung Tsim},
  journal={Journal of agricultural and food chemistry},
  year={2007},
  volume={55 6},
  pages={
          2438-45
        }
}
Despite the classical hormonal effect, estrogen possesses a neuroprotective effect in the brain, which has led many to search for novel treatments for neurodegenerative diseases. Flavonoids, a group of compounds mainly derived from vegetables, share a resemblance, chemically, to estrogen, and indeed, some have been used as estrogen substitutes. To search for potential therapeutic agents against neurodegenerative diseases, different subclasses of flavonoids were analyzed and compared with… CONTINUE READING
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