Flavonoids, leucocyte migration and eicosanoids.

Abstract

Quercetin reduced the concentration of prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) in the pleural exudate induced in rats by 1% carrageenan given intrapleurally. Leucocyte migration in the exudate was also reduced by the flavonoid. Inhibition of eicosanoids and leucocytes in the exudate was dose-related. Quercetin also reduced LTB4 synthesis in cells… (More)

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@article{Mascolo1988FlavonoidsLM, title={Flavonoids, leucocyte migration and eicosanoids.}, author={Nicola Mascolo and Ant{\'o}nio Pinto and Francesco Capasso}, journal={The Journal of pharmacy and pharmacology}, year={1988}, volume={40 4}, pages={293-5} }