Flavonoids from Artemisia annua L. as antioxidants and their potential synergism with artemisinin against malaria and cancer.

@article{Ferreira2010FlavonoidsFA,
  title={Flavonoids from Artemisia annua L. as antioxidants and their potential synergism with artemisinin against malaria and cancer.},
  author={Jorge F. S. Ferreira and Devanand L. Luthria and Tomikazu Sasaki and Arne Heyerick},
  journal={Molecules},
  year={2010},
  volume={15 5},
  pages={3135-70}
}
Artemisia annua is currently the only commercial source of the sesquiterpene lactone artemisinin.Since artemisinin was discovered as the active component of A. annua in early 1970s, hundreds of papers have focused on the anti-parasitic effects of artemisinin and its semi-synthetic analogs dihydroartemisinin, artemether, arteether, and artesunate. Artemisinin per se has not been used in mainstream clinical practice due to its poor bioavailability when compared to its analogs. In the past decade… CONTINUE READING
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