Flavonoids as acetylcholinesterase inhibitors: Current therapeutic standing and future prospects.

@article{Khan2018FlavonoidsAA,
  title={Flavonoids as acetylcholinesterase inhibitors: Current therapeutic standing and future prospects.},
  author={Haroon Khan and Marya and Surriya Amin and Mohammad Amjad Kamal and Seema Patel},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2018},
  volume={101},
  pages={
          860-870
        }
}
BACKGROUND Acetylcholinesterase (AChE), a serine hydrolase, is primarily responsible for the termination of signal transmission in the cholinergic system, owing to its outstanding hydrolyzing potential. Its substrate acetylcholine (ACh), is a neurotransmitter of the cholinergic system, with a predominant effect on motor neurons involved in memory formation. So, by decreasing the activity of this enzyme by employment of specific inhibitors, a number of motor neuron disorders such as myasthenia… CONTINUE READING

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