Flavonoid derivative 7,8-DHF attenuates TBI pathology via TrkB activation.

Abstract

Traumatic brain injury (TBI) is followed by a state of metabolic dysfunction, affecting the ability of neurons to use energy and support brain plasticity; there is no effective therapy to counteract the TBI pathology. Brain-derived neurotrophic factor (BDNF) has an exceptional capacity to support metabolism and plasticity, which highly contrasts with its… (More)
DOI: 10.1016/j.bbadis.2015.01.018

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