Flavonoid, morin inhibits oxidative stress, inflammation and enhances neurotrophic support in the brain of streptozotocin-induced diabetic rats

@article{Ola2014FlavonoidMI,
  title={Flavonoid, morin inhibits oxidative stress, inflammation and enhances neurotrophic support in the brain of streptozotocin-induced diabetic rats},
  author={Mohammad Shamsul Ola and Abdulaziz Mohamed Aleisa and Salim Salih Al-Rejaie and Hatem M Abuohashish and Mihir Yogeshkumar Parmar and Abdullah S. Alhomida and Mohammed Meraj Ahmed},
  journal={Neurological Sciences},
  year={2014},
  volume={35},
  pages={1003-1008}
}
Diabetes-induced damages in brain are known as diabetic encephalopathy, which is well characterized by cellular, molecular and functional changes in the brain of diabetic subjects and rodents. However, little is known about the mechanism of damages and the therapeutic strategies in ameliorating those damages in the diabetic brain. In this study, we utilized a flavonoid, morin which is emerging as a potent drug against a wide range of free radical-mediated as well as neurodegenerative diseases… CONTINUE READING