Flavone is efficient to protect zebrafish fins from UV-induced damage.

  title={Flavone is efficient to protect zebrafish fins from UV-induced damage.},
  author={I-Ting Tsai and Zhi-Shiang Yang and Zi-Yu Lin and Chi-Chung Wen and C W Cheng and Yau-Hung Chen},
  journal={Drug and chemical toxicology},
  volume={35 3},
We used ultraviolet (UV)-induced fin damage in zebrafish as a system for evaluating the chemopreventive potential of flavonoids. Chemopreventive effects of each compound, including flavone, flavanone, and chalcone, on fin development were evaluated using Kaplan-Meier analysis and Cox proportional hazards regression. Results showed that 1) flavone has the highest capacity to protect zebrafish fins from UV-induced damages among other groups; 2) zebrafish fins in the UV+1 ppm flavone group are 1… CONTINUE READING


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