Flavodoxin mutants of Escherichia coli K-12.

  title={Flavodoxin mutants of Escherichia coli K-12.},
  author={Philippe Gaudu and Birgit Weiss},
  journal={Journal of bacteriology},
  volume={182 7},
The flavodoxins are flavin mononucleotide-containing electron transferases. Flavodoxin I has been presumed to be the only flavodoxin of Escherichia coli, and its gene, fldA, is known to belong to the soxRS (superoxide response) oxidative stress regulon. An insertion mutation of fldA was constructed and was lethal under both aerobic and anaerobic conditions; only cells that also had an intact (fldA(+)) allele could carry it. A second flavodoxin, flavodoxin II, was postulated, based on the… CONTINUE READING


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