Flavin-dependent alkyl hydroperoxide reductase from Salmonella typhimurium. 2. Cystine disulfides involved in catalysis of peroxide reduction.

@article{Poole1996FlavindependentAH,
  title={Flavin-dependent alkyl hydroperoxide reductase from Salmonella typhimurium. 2. Cystine disulfides involved in catalysis of peroxide reduction.},
  author={Leslie B. Poole},
  journal={Biochemistry},
  year={1996},
  volume={35 1},
  pages={65-75}
}
The two-component alkyl hydroperoxide reductase enzyme system from Salmonella typhimurium catalyzes the pyridine nucleotide-dependent reduction of alkyl hydroperoxide and hydrogen peroxide substrates. This system is composed of a flavoenzyme, AhpF, which is related to the disulfide-reducing enzyme thioredoxin reductase, and a smaller protein, AhpC, which lacks a chromophoric cofactor. We have demonstrated that NADH-linked reduction of AhpF under anaerobic conditions converts two cystine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 74 extracted citations

References

Publications referenced by this paper.
Showing 1-2 of 2 references

inFlaVins and FlaVoproteins 1993(Yagi, K., Ed.) pp 583-586

  • L. B. Poole
  • Nature 352,
  • 1994
Highly Influential
5 Excerpts

inChemistry and Biochemistry of FlaVoenzymes(Müller, F., Ed.) pp

  • H C., Jr.
  • Mol. Microbiol
  • 1992

Similar Papers

Loading similar papers…