Flare and tumor lysis syndrome with atypical features after letrozole therapy in advanced breast cancer. A case report.

@article{Zigrossi2001FlareAT,
  title={Flare and tumor lysis syndrome with atypical features after letrozole therapy in advanced breast cancer. A case report.},
  author={Paola Zigrossi and Maddalena Brustia and Flavio Bobbio and Mauro Campanini},
  journal={Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna},
  year={2001},
  volume={16 2},
  pages={112-7}
}
Tumor lysis syndrome, which develops after effective therapy of malignant conditions and leads to hyperuricemia, hyperkaliemia, hyperphosphatemia, hypocalcemia and elevated lactate dehydrogenase, is uncommon in solid tumors. In breast carcinoma it can be associated with tamoxifen flare, i.e. a transient increase in symptoms, mainly bone pain, observed… CONTINUE READING