Flagellate dermatitis as a bleomycin-specific adverse effect of cytostatic therapy: a clinical-histopathologic correlation.

@article{Ziemer2011FlagellateDA,
  title={Flagellate dermatitis as a bleomycin-specific adverse effect of cytostatic therapy: a clinical-histopathologic correlation.},
  author={Mirjana Ziemer and Steven Goetze and Katalin Juh{\'a}sz and Peter Elsner},
  journal={American journal of clinical dermatology},
  year={2011},
  volume={12 1},
  pages={68-76}
}
In oncology, bleomycin is a frequently used drug for the treatment of several malignancies. In particular, it is part of chemotherapy protocols in testicular cancer. We report on two patients with testicular cancer who received bleomycin-including chemotherapy and developed flagellate dermatitis. This is a typical adverse effect of bleomycin therapy; however, its pathophysiology has not yet been clarified. We discuss possible pathophysiologic mechanisms for this reaction. In general, it has… CONTINUE READING

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