Flagellar pocket restructuring through the Leishmania life cycle involves a discrete flagellum attachment zone

@inproceedings{Wheeler2016FlagellarPR,
  title={Flagellar pocket restructuring through the Leishmania life cycle involves a discrete flagellum attachment zone},
  author={Richard John Wheeler and Jack Daniel Sunter and Keith Gull},
  booktitle={Journal of cell science},
  year={2016}
}
Leishmania promastigote parasites have a flagellum, which protrudes from the flagellar pocket at the cell anterior, yet, surprisingly, have homologs of many flagellum attachment zone (FAZ) proteins--proteins used in the related Trypanosoma species to laterally attach the flagellum to the cell body from the flagellar pocket to the cell posterior. Here, we use seven Leishmania mexicana cell lines that expressed eYFP fusions of FAZ protein homologs to show that the Leishmania flagellar pocket… CONTINUE READING
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