Fixed-dose combinations of antituberculous medications to prevent drug resistance.

@article{Moulding1995FixeddoseCO,
  title={Fixed-dose combinations of antituberculous medications to prevent drug resistance.},
  author={Thomas S Moulding and Asim K. Dutt and Lee B. Reichman},
  journal={Annals of internal medicine},
  year={1995},
  volume={122 12},
  pages={951-4}
}
The treatment of tuberculosis requires at least two drugs to retard the development of drug resistance. Unfortunately, patients may take only one drug (monotherapy) when more than one is prescribed. Fixed-dose combinations with two or more antituberculous drugs in one capsule or tablet are available to prevent this. In the United States, these drugs are Rifamate (Marion Merrell Dow), which contains isoniazid plus rifampin, and Rifater (Marion Merrell Dow), which contains isoniazid plus rifampin… CONTINUE READING