Fixation probability of mobile genetic elements such as plasmids.

  title={Fixation probability of mobile genetic elements such as plasmids.},
  author={Samuel John Tazzyman and Sebastian Bonhoeffer},
  journal={Theoretical population biology},
Mobile genetic elements such as plasmids are increasingly becoming thought of as evolutionarily important. Being horizontally transmissible is generally assumed to be beneficial for a gene. Using several simple modelling approaches we show that in fact being horizontally transferable is just as important for fixation as being beneficial to the host, in line with other results. We find fixation probability is approximately 2(s+β), where s is the increased (vertical) fitness provided by the gene… CONTINUE READING
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On probability of fixation of mutant genes in a population

  • M. Kimura
  • Genetics
  • 1962
Highly Influential
8 Excerpts

A mathematical theory of natural and artificial selection, Part V: selection and mutation

  • J.B.S. Haldane
  • Proceedings of the Cambridge Philosophical…
  • 1927
Highly Influential
10 Excerpts

Mathematical modeling of evolution of horizontally transferred genes

  • Novozhilov, S Artem, Karev, P Georgy, Koonin, V Eugene
  • Molecular Biology and Evolution
  • 2005
Highly Influential
4 Excerpts

Lateral gene transfer and the nature of bacterial innovation

  • Ochman, Howard, Lawrence, G Jeffrey, Groisman, A Eduardo
  • Nature
  • 2000
Highly Influential
4 Excerpts

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