Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease.

@article{Krack2003FiveyearFO,
  title={Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease.},
  author={Paul Krack and Alina Batir and Nad{\'e}ge Van Blercom and St{\'e}phan Chabard{\`e}s and Val{\'e}rie Fraix and Claire Ardouin and Adnan Koudsi{\'e} and Patricia Dowsey Limousin and Abdelhamid Benazzouz and Jean François Lebas and Alim-Louis Benabid and Pierre Pollak},
  journal={The New England journal of medicine},
  year={2003},
  volume={349 20},
  pages={1925-34}
}
BACKGROUND Although the short-term benefits of bilateral stimulation of the subthalamic nucleus in patients with advanced Parkinson's disease have been well documented, the long-term outcomes of the procedure are unknown. METHODS We conducted a five-year prospective study of the first 49 consecutive patients whom we treated with bilateral stimulation of the subthalamic nucleus. Patients were assessed at one, three, and five years with levodopa (on medication) and without levodopa (off… CONTINUE READING
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Unified Parkinson’s Copyright

  • S Fahn, RL Elton
  • Massachusetts Medical Society. All rights…
  • 2003

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