Five month study of percutaneous heart valves in the systemic circulation of sheep using a novel model of aortic insufficiency.

@article{Eltchaninoff2006FiveMS,
  title={Five month study of percutaneous heart valves in the systemic circulation of sheep using a novel model of aortic insufficiency.},
  author={H{\'e}l{\`e}ne Eltchaninoff and Danielle Nusimovici-Avadis and Vasilis C. Babaliaros and Benjamin Spenser and Bella Felsen and Alain G Cribier},
  journal={EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology},
  year={2006},
  volume={1 4},
  pages={438-44}
}
AIMS To study the 5 month performance of a balloon-expandable percutaneous heart valve (PHV) in the systemic circulation of animals. METHODS AND RESULTS Moderate-to-severe (>/= grade 3) aortic insufficiency was created in 14 juvenile sheep using a bioptome device. A 23mm PHV was implanted distal to the left subclavian artery (1.78+/-0.18 cm2 area, 27+/-2 mmHg closing gradient). Valve performance was followed angiographically (baseline, 21 weeks) and echocardiographically (baseline, 6, 14, 21… CONTINUE READING