Corpus ID: 14180028

Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature.

@article{Chang1999FiveDA,
  title={Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature.},
  author={S. S. Chang and V. Reuter and W. Heston and N. Bander and L. Grauer and P. B. Gaudin},
  journal={Cancer research},
  year={1999},
  volume={59 13},
  pages={
          3192-8
        }
}
  • S. S. Chang, V. Reuter, +3 authors P. B. Gaudin
  • Published 1999
  • Medicine
  • Cancer research
  • Prostate-specific membrane antigen (PSMA) is a type II integral membrane glycoprotein that was initially characterized by the monoclonal antibody (mAb) 7E11. [...] Key Method We examined the immunohistochemical characteristics of 7E11 and those of four recently developed anti-PSMA mAbs (J591, J415, and Hybritech PEQ226.5 and PM2J004.5), each of which binds a distinct epitope of PSMA.Expand Abstract

    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    This was a multicenter, multi-reader, open-label, Phase 2 study assessing the safety and performance characteristics of MIP 1404 imaging in the detection of prostate gland and pelvic… Expand
    ConditionsProstate Cancer
    InterventionDrug
    Prostate-Specific Membrane Antigen-Based Therapeutics
    • 64
    • Open Access
    PSMA specific antibodies and their diagnostic and therapeutic use
    • 53

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