Five Sesquiterpenoids from a Marine-Derived Fungus Aspergillus sp. Isolated from a Gorgonian Dichotella gemmacea

@article{Wei2010FiveSF,
  title={Five Sesquiterpenoids from a Marine-Derived Fungus Aspergillus sp. Isolated from a Gorgonian Dichotella gemmacea},
  author={Mei-Yan Wei and Chang-Yun Wang and Qing-Ai Liu and Chang‐Lun Shao and Zhigang She and Yong‐cheng Lin},
  journal={Marine Drugs},
  year={2010},
  volume={8},
  pages={941 - 949}
}
Three new phenolic bisabolane-type sesquiterpenoids: (+)-methyl sydowate (1), 7-deoxy-7,14-didehydrosydonic acid (2), and 7-deoxy-7,8-didehydrosydonic acid (3), together with two known fungal metabolites were isolated from the fermentation broth of a marine-derived fungus Aspergillus sp., which was isolated in turn from a gorgonian Dichotella gemmacea collected from the South China Sea. Their structures were elucidated by combined spectroscopic methods, and the structure of 1 was further… 
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References

SHOWING 1-10 OF 29 REFERENCES

New cytotoxic sesquiterpenoid nitrobenzoyl esters from a marine isolate of the fungus Aspergillus versicolor

Bioactive sesquiterpenes from a Taiwanese marine sponge Parahigginsia sp.

Five new sesquiterpenes, parahigginols A-D (1-4) and parahigginic acid (5), have been isolated from a Taiwanese marine sponge Parahigginsia sp. The structural assignments of the new compounds were…

Structures and synthesis of some new antibacterial sesquiterpenoids from the gorgonian coral Pseudopterogorgia rigida

Speradine A, a new pentacyclic oxindole alkaloid from a marine-derived fungus Aspergillus tamarii

Aspergillamides A and B: Modified cytotoxic tripeptides produced by a marine fungus of the genus Aspergillus

Isolation, Structural Elucidation, and Synthesis of Curcutetraol

The new natural products (+)-curcutetraol and (−)-curcutriolamide were isolated from the bacterium CNH-741 and the fungus CNC-979, isolated from marine sediment. (+)-Curcutetraol is a polar compound…

Two New Metabolites, Sydonic Acid and Hydroxysydonic Acid, from Aspergillus sydowi

From the culture filtrates of Aspergillus sydowi two new metabolites, designated as sydonic acid and hydroxysydonic acid, have been isolated. Sydonic acid, C15H22O4, forms colorless needles, mp…

Cottoquinazoline A and cotteslosins A and B, metabolites from an Australian marine-derived strain of Aspergillus versicolor.

An Australian marine-derived isolate of Aspergillus versicolor (MST-MF495) yielded the known fungal metabolites sterigmatocystin, violaceol I, violaceol II, diorcinol, (-)-cyclopenol, and…

Presence of Aspergillus sydowii, a pathogen of gorgonian sea fans in the marine sponge Spongia obscura

It is suggested that sponges have the possibility of being reservoirs of a potential marine pathogen and the capacity of this fungus to persist in sponge environment is shown.

Isolation and Absolute Stereochemistry of Optically Active Sydonic Acid from Glonium sp. (Hysteriales, Ascomycota)

Optically active sydonic acid (1) was isolated for the first time from a culture broth of Glonium sp. The absolute stereochemistry was established to be (S) by comparing the circular dichroism (CD)…