Fitness costs of Doc expression are insufficient to stabilize its copy number in Drosophila melanogaster.

@article{Yang2003FitnessCO,
  title={Fitness costs of Doc expression are insufficient to stabilize its copy number in Drosophila melanogaster.},
  author={H. Yang and Sergey V. Nuzhdin},
  journal={Molecular biology and evolution},
  year={2003},
  volume={20 5},
  pages={
          800-4
        }
}
The stable coexistence of transposable elements (TEs) with their host genome over long periods of time suggests TEs have to impose some deleterious effect upon their host fitness. Three mechanisms have been proposed to account for the deleterious effect caused by TEs: host gene interruptions by TE insertions, chromosomal rearrangements by TE-induced ectopic recombination, and costly TE expression. However, the relative importance of these mechanisms remains controversial. Here, we test… CONTINUE READING

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