Fission yeast Swi5 protein, a novel DNA recombination mediator.

  title={Fission yeast Swi5 protein, a novel DNA recombination mediator.},
  author={Nami Haruta and Yufuko Akamatsu and Yasuhiro Tsutsui and Yumiko Kurokawa and Yasuto Murayama and Benoit Arcangioli and Hiroshi Iwasaki},
  journal={DNA repair},
  volume={7 1},
The Schizosaccharomyces pombe Swi5 protein forms two distinct protein complexes, Swi5-Sfr1 and Swi5-Swi2, each of which plays an important role in the related but functionally distinct processes of homologous recombination and mating-type switching, respectively. The Swi5-Sfr1 mediator complex has been shown to associate with the two RecA-like recombinases, Rhp51 (spRad51) and Dmc1, and to stimulate in vitro DNA strand exchange reactions mediated by these proteins. Genetic analysis indicates… CONTINUE READING


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