Fission yeast Rap1 homolog is a telomere-specific silencing factor and interacts with Taz1p.

@article{Park2002FissionYR,
  title={Fission yeast Rap1 homolog is a telomere-specific silencing factor and interacts with Taz1p.},
  author={Min Jung Park and Yeun Kyu Jang and Eun Shik Choi and Hyun Soo Kim and Sang Dai Park},
  journal={Molecules and cells},
  year={2002},
  volume={13 2},
  pages={327-33}
}
Taz1p is the fission yeast orthologue of human TRF2, a telomeric repeat-binding protein. Delta(taz1) mutants are defective in telomeric silencing, telomere length control, and meiotic recombination events. A recent report demonstrated that the human Rap1p homolog (hRap1) is recruited to telomere by interaction with TRF2, arguing that the telomere control mechanism of higher eukaryotes is distinct from that of the budding yeast. Taz1p showed a significant similarity to human TRF2, but not with… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…