Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis.

@article{Kanai2005FissionYM,
  title={Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis.},
  author={Muneyoshi Kanai and Kazunori Kume and Kohji Miyahara and Keisuke Sakai and Keigo Nakamura and Klaus Leonhard and David J. Wiley and Fulvia Verde and Takashi Toda and D. B. Hirata},
  journal={The EMBO journal},
  year={2005},
  volume={24 17},
  pages={3012-25}
}
Cell morphogenesis is of fundamental significance in all eukaryotes for development, differentiation, and cell proliferation. In fission yeast, Drosophila Furry-like Mor2 plays an essential role in cell morphogenesis in concert with the NDR/Tricornered kinase Orb6. Mutations of these genes result in the loss of cell polarity. Here we show that the conserved proteins, MO25-like Pmo25, GC kinase Nak1, Mor2, and Orb6, constitute a morphogenesis network that is important for polarity control and… CONTINUE READING