Fishing for Answers with Transposons

  title={Fishing for Answers with Transposons},
  author={Shannon A. Wadman and Karl J. Clark and Perry B. Hackett},
  journal={Marine Biotechnology},
Transposons are one means that nature has used to introduce new genetic material into chromosomes of organisms from every kingdom. They have been extensively used in prokaryotic and lower eukaryotic systems, but until recently there was no transposon that had significant activity in vertebrates. The Sleeping Beauty (SB) transposon system was developed to direct the integration of precise DNA sequences into chromosomes. The SB system was derived from salmonid sequences that had been inactive for… CONTINUE READING