Fishing With (Proto)Net—A Principled Approach to Protein Target Selection

  • Michal Linial
  • Published 2003 in Comparative and functional genomics

Abstract

Structural genomics strives to represent the entire protein space. The first step towards achieving this goal is by rationally selecting proteins whose structures have not been determined, but that represent an as yet unknown structural superfamily or fold. Once such a structure is solved, it can be used as a template for modelling homologous proteins. This… (More)
DOI: 10.1002/cfg.328

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