Fisher information analysis of list-mode SPECT emission data for joint estimation of activity and attenuation distribution

@article{Rahman2018FisherIA,
  title={Fisher information analysis of list-mode SPECT emission data for joint estimation of activity and attenuation distribution},
  author={Md Ashequr Rahman and Yansong Zhu and Eric Clarkson and Matthew A. Kupinski and Eric C. Frey and Abhinav K. Jha},
  journal={Inverse Problems},
  year={2018},
  volume={36}
}
The potential to perform attenuation and scatter compensation (ASC) in single-photon emission computed tomography (SPECT) without a separate transmission scan is highly significant. In this context, attenuation in SPECT is primarily due to Compton scattering, where the probability of Compton scatter is proportional to the attenuation coefficient of the tissue and the energy of the scattered photon and the scattering angle are related. Based on this premise, we investigated whether the SPECT… 
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18 Citations
Background Citations
6
Methods Citations
3

18 Citations

A LIST-MODE OSEM-BASED ATTENUATION AND SCATTER COMPENSATION METHOD FOR SPECT

A reconstruction method that uses the entire SPECT emission data, i.e. data in both the photopeak and scatter windows, acquired in list-mode format and including the energy attribute of the detected photon, to perform ASC is developed.

A physics and learning-based transmission-less attenuation compensation method for SPECT.

A physics and learning-based method that uses the SPECT emission data in the photopeak and scatter windows to perform transmission-less AC in SPECT and visually, the images reconstructed using the proposed method looked similar to those with the true attenuation map.

Task-based assessment of binned and list-mode SPECT systems

This study quantitatively investigated whether processing data in LM format, and in particular, the energy attribute of the detected photon, provides improved performance on the task of absolute quantification of region-of-interest (ROI) uptake in comparison to processing the data in binned format.

Deep learning-based attenuation map generation for myocardial perfusion SPECT

A deep convolutional neural network is developed to estimate attenuation maps for SPECT directly from the emission data using deep learning methods and is capable of generating highly reliable attenuation Maps to facilitate attenuation correction forSPECT-only scanners for myocardial perfusion imaging.

Development and task-based evaluation of a scatter-window projection and deep learning-based transmission-less attenuation compensation method for myocardial perfusion SPECT

A Scatter-window projection and deep Learning-based AC (SLAC) method to perform AC without a separate transmission scan is developed and objectively evaluated on the clinical task of detecting perfusion defects on MPI.

Attenuation Correction for Dedicated Cardiac SPECT Imaging Without Using Transmission Data

This study presented a new method for generating an attenuation map directly from emission data by segmentation of precisely non-rigid registration extended cardiac-torso (XCAT)-digital phantom with cardiac SPECT images to precisely segment the contour of organs.

Direct and indirect strategies of deep-learning-based attenuation correction for general purpose and dedicated cardiac SPECT

This work developed strategies of generating μ-maps for dedicated cardiac SPECT with small FOV and found that indirect approaches showed superior performance of AC than direct approaches.

CT-free attenuation correction for dedicated cardiac SPECT using a 3D dual squeeze-and-excitation residual dense network

A deep learning-based approach to generate synthetic AC images from SPECT images without AC using a customized Dual Squeeze-and-Excitation Residual Dense Network showed superior performance to conventional network design such as U-Net.

Attenuation correction using deep learning for brain perfusion SPECT images

An auto-encoder (AE) using a CNN to correct the attenuation in brain perfusion SPECT images is constructed and yields highly accurate attenuation-corrected brain perfusionsSPECT images.

A Projection-Domain Low-Count Quantitative SPECT Method for ɑ-Particle-Emitting Radiopharmaceutical Therapy

A low-count quantitative SPECT (LC-QSPECT) method that directly estimates the regional activity uptake from the projection data, compensates for stray-radiation-related noise, and accounts for the radioisotope and SPECT physics, including the isotope spectra, scatter, attenuation, and collimator-detector response, using a Monte Carlo-based approach is developed.

References

SHOWING 1-10 OF 75 REFERENCES

Joint reconstruction of activity and attenuation map using LM SPECT emission data

This paper investigates the possibility of joint reconstruction of the activity and attenuation map using list- mode (LM) SPECT emission data, including the scattered-photon data, and proposes a path-based formalism to process scattered- photon data.

A LIST-MODE OSEM-BASED ATTENUATION AND SCATTER COMPENSATION METHOD FOR SPECT

A reconstruction method that uses the entire SPECT emission data, i.e. data in both the photopeak and scatter windows, acquired in list-mode format and including the energy attribute of the detected photon, to perform ASC is developed.

An EM algorithm for estimating SPECT emission and transmission parameters from emission data only

EM-IntraSPECT provided more uniform estimates of cardiac activity in the physical phantom study and in the simulation study with tight support, but less uniform estimates with a broad support, and the new EM algorithm derived here has additional applications, including reconstructing emission and transmission projection data under a unified statistical model.

Simultaneous maximum a posteriori reconstruction of attenuation and activity distributions from emission sinograms

A new method to compute an attenuation map directly from the emission sinogram, eliminating the transmission scan from the acquisition protocol is proposed, which has been tested on mathematical phantoms and on a few clinical studies.

Attenuation correction using SPECT emission data only

A major step towards quantitative SPECT imaging may be achieved if tissue attenuation and scatter effects are accounted for in the image reconstruction process. The current trend is to calculate the…

Use of measured scatter data for the attenuation correction of single photon emission tomography without transmission scanning.

The technique presented shows promise as a method of attenuation correction for SPECT data without the need for a separate transmission scan and produces results that represent a promising first step toward the use of scatter data to estimate the activity distribution and attenuation map from single photon emission tomography (SPECT) data without a transmission scan.

Attenuation map estimation with SPECT emission data only

A new method to estimate the attenuation map using the data consistency conditions of the attenuated Radon transform is proposed, based on deriving boundaries of the constant regions of the true attenuations map using an iterative algorithm.

Estimating ROI activity concentration with photon-processing and photon-counting SPECT imaging systems

The effects of varying the size of the ROI and varying the number of bins for the attribute corresponding to the angular orientation of the detector in a continuously rotating SPECT system are investigated and results indicate that in several cases, PP systems offer improved estimation performance compared to PC systems.

A transmission-map-based scatter correction technique for SPECT in inhomogeneous media.

This method is based on the use of a transmission map to define the inhomogeneous scattering object and uses the set of line integrals calculated as part of the attenuation correction technique, as the basis of a model of the distribution of scattered events.

Segmentation of the body and lungs from Compton scatter and photopeak window data in SPECT: a Monte-Carlo investigation

The authors proposed a method to segment such regions from the Compton scatter and photopeak window SPECT slices of Tc-99m Sestamibi studies, and demonstrated reasonable contrast could be obtained from Compton scatter data for the segmentation of the lung regions.
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