Fish oils and low-molecular-weight heparin for the reduction of restenosis after percutaneous transluminal coronary angioplasty. The EMPAR Study.

@article{Cairns1996FishOA,
  title={Fish oils and low-molecular-weight heparin for the reduction of restenosis after percutaneous transluminal coronary angioplasty. The EMPAR Study.},
  author={John Cairns and Jaswinder Gill and Brian Morton and Robert Roberts and Michael J. Gent and Jack Hirsh and Doug Holder and Keith J. C. Finnie and J F Marquis and Shahid Naqvi and Eric E. Cohen},
  journal={Circulation},
  year={1996},
  volume={94 7},
  pages={1553-60}
}
BACKGROUND Percutaneous transluminal coronary angioplasty (PTCA) is complicated by restenosis within 6 months in > 40% of patients. Theoretical, animal experimental, and human epidemiological and clinical trial findings have suggested that fish oils (n-3) might reduce restenosis. Low-molecular-weight heparin (LMWH) has reduced cellular proliferation and restenosis in several experimental systems. METHODS AND RESULTS We randomized 814 patients to fish oils (5.4 g n-3 fatty acids) or placebo a… CONTINUE READING
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