Fish oil prevents rodent anxious states comorbid with diabetes: A putative involvement of nitric oxide modulation.

@article{Siba2017FishOP,
  title={Fish oil prevents rodent anxious states comorbid with diabetes: A putative involvement of nitric oxide modulation.},
  author={Isadora Pozzetti Siba and M Bortolanza and Maria Aparecida Barbato Fraz{\~a}o Vital and Roberto Andreatini and Joice Maria da Cunha and Elaine Del Bel and Jana{\'i}na Menezes Zanoveli},
  journal={Behavioural brain research},
  year={2017},
  volume={326},
  pages={173-186}
}
There is an urgent need to understand the pathophysiological mechanisms related to anxiety associated with diabetes, seeking more effective alternative treatments to treat it. For that, the effect of a preventive and prolonged treatment with fish oil (FO), a source of omega-3 polyunsaturated fatty acid, was tested in streptozotocin-diabetic (DBT) rats submitted to the anxiety tests. Additionally, an immunohistochemistry for neuronal NO synthase (nNOS) was performed in brain areas related to… CONTINUE READING
2 Citations
88 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 88 references

Kurhe.;1; Insulin reverses anxiety-like behavior evoked by streptozotocin-induced diabetes in mice

  • D. Gupta, Y. M. Radhakrishnan
  • Metab Brain Dis
  • 2014
Highly Influential
5 Excerpts

Zanoveli.;1; Increased oxidative stress in prefrontal cortex and hippocampus is related to depressive-like behavior in streptozotocin-diabetic rats

  • H. de Morais, C. P. de Souza, +4 authors J.M.J.M. da Cunha
  • Behav Brain Res
  • 2013
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…