Fish Short-Term Reproductive Assay for Evaluating the Estrogenic Property of a Commonly used Antioxidant, Butylated Hydroxyanisole

  title={Fish Short-Term Reproductive Assay for Evaluating the Estrogenic Property of a Commonly used Antioxidant, Butylated Hydroxyanisole},
  author={George Paul and R. N. Binitha and Francis Sunny},
  journal={Current Science},
Fish short-term reproductive assay (FSTRA) is a tier one assay for screening the endocrine disrupting property of a compound. This study analysed the end points like variations in Gonado–Somatic index (GSI), sperm quality and count, serum hormone levels (FSH, LH, estrogen and testosterone) to study the endocrine disrupting properties of butylated hydroxyanisole (BHA). A fresh water teleost, Anabas testudineus was used as animal model in this study. LC50 value of BHA was 250 mg/kg body weight in… 
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