Fish Oil-Rich Diet Promotes Hematopoiesis and Alters Hematopoietic Niche.

@article{Xia2015FishOD,
  title={Fish Oil-Rich Diet Promotes Hematopoiesis and Alters Hematopoietic Niche.},
  author={S Xia and Xiao-ping Li and Lu Cheng and Mu-tian Han and Miao-miao Zhang and Qi-Xiang Shao and Hua-xi Xu and Ling Qi},
  journal={Endocrinology},
  year={2015},
  volume={156 8},
  pages={
          2821-30
        }
}
The self-renewal and differentiation of hematopoietic stem cells (HSCs) in bone marrow are essential to replenish all blood cell types, but how this process is influenced by diet remains largely unclear. Here we show that a diet rich in fish oils promotes self-renewal of HSCs and extramedullary hematopoiesis. Chronic intake of a fish oil-rich diet increases the abundance of HSCs, alters the hematopoietic microenvironment, and, intriguingly, induces the expression of matrix metalloproteinase 12… CONTINUE READING
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