Fish Oil Reduces Hepatic Injury by Maintaining Normal Intestinal Permeability and Microbiota in Chronic Ethanol-Fed Rats.

  title={Fish Oil Reduces Hepatic Injury by Maintaining Normal Intestinal Permeability and Microbiota in Chronic Ethanol-Fed Rats.},
  author={Jiun Rong Chen and Ya-Ling Chen and Hsiang-Chi Peng and Yu-An Lu and Hsiao-Li Chuang and Hsiao-Yun Chang and Hsiao-Yun Wang and Yu-Ju Su and Suh-Ching Yang},
  journal={Gastroenterology research and practice},
The aim of this study was to investigate the ameliorative effects of fish oil on hepatic injury in ethanol-fed rats based on the intestinal permeability and microbiota. Rats were assigned to 6 groups and fed either a control diet or an ethanol diet such as C (control), CF25 (control with 25% fish oil), CF57 (control with 57% fish oil), E (ethanol), EF25 (ethanol with 25% fish oil), and EF57 (ethanol with 57% fish oil) groups. Rats were sacrificed at the end of 8 weeks. Plasma aspartate… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 49 references


S. Ghosh, D. DeCoffe
Brown et al., “Fish oil attenuates omega-6 polyunsaturated fatty acid-induced dysbiosis and infectious colitis but impairs LPS dephosphorylation activity causing sepsis,” PLoS ONE, vol. 8, no. 2, Article ID e55468 • 2013
View 11 Excerpts
Highly Influenced

and E

L.E.M. Willemsen, M. A. Koetsier, M. Balvers, C. Beermann, B. Stahl
A. F. van Tol, “Polyunsaturated fatty acids support epithelial barrier integrity and reduce IL-4 mediated permeability in vitro,” European Journal of Nutrition, vol. 47, no. 4, pp. 183–191 • 2008
View 3 Excerpts
Highly Influenced

Alcohol-induced oxidative stress.

View 9 Excerpts
Highly Influenced

Recent Advances in Alcoholic Liver Disease I. Role of intestinal permeability and endotoxemia in alcoholic liver disease.

American journal of physiology. Gastrointestinal and liver physiology • 2004
View 10 Excerpts
Highly Influenced


M. Criado-Jiménez, L. Rivas-Cabañero
A. Mart́ın-Oterino, J. M. López-Novoa, and A. Sánchez-Rodŕıguez, “Nitric oxide production by mononuclear leukocytes in alcoholic cirrhosis,” Journal of Molecular Medicine, vol. 73, no. 1, pp. 31–33 • 1995
View 9 Excerpts
Highly Influenced

Nitric oxide production by monocytes in alcoholic liver disease.

Journal of hepatology • 1992
View 9 Excerpts
Highly Influenced

andD.A.Cohen, “Increased tumor necrosis factor production by monocytes in alcoholic hepatitis,

Hepatology, vol. 9, • 1989
View 9 Excerpts
Highly Influenced

Epidermal growth factor improved alcohol-induced inflammation in rats,

Y.-L. Chen, H.-C. Peng, Y.-C.Hsieh, S.-C. Yang
Alcohol, vol. 48, • 2014
View 2 Excerpts


L.-L. Huang, J.-B. Wan
Wang et al., “Suppression of acute ethanol-induced hepatic steatosis by docosahexaenoic acid is associated with downregulation of stearoyl-CoA desaturase 1 and inflammatory cytokines,” Prostaglandins Leukotrienes and Essential Fatty Acids, vol. 88, no. 5, pp. 347–353 • 2013
View 3 Excerpts

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