Fish Oil Decreases Hepatic Lipogenic Genes in Rats Fasted and Refed on a High Fructose Diet

@inproceedings{Castro2015FishOD,
  title={Fish Oil Decreases Hepatic Lipogenic Genes in Rats Fasted and Refed on a High Fructose Diet},
  author={Gabriela Salim Ferreira de Castro and Jo{\~a}o Felipe Rito Cardoso and Philip C Calder and Alceu Afonso Jord{\~a}o and Helio Vannucchi},
  booktitle={Nutrients},
  year={2015}
}
Fasting and then refeeding on a high-carbohydrate diet increases serum and hepatic triacylglycerol (TAG) concentrations compared to standard diets. Fructose is a lipogenic monosaccharide which stimulates de novo fatty acid synthesis. Omega-3 (n-3) fatty acids stimulate hepatic β-oxidation, partitioning fatty acids away from TAG synthesis. This study investigated whether dietary n-3 fatty acids from fish oil (FO) improve the hepatic lipid metabolic response seen in rats fasted and then refed on… CONTINUE READING

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