Fisetin improves glucose homeostasis through the inhibition of gluconeogenic enzymes in hepatic tissues of streptozotocin induced diabetic rats.

@article{Prasath2014FisetinIG,
  title={Fisetin improves glucose homeostasis through the inhibition of gluconeogenic enzymes in hepatic tissues of streptozotocin induced diabetic rats.},
  author={Gopalan Sriram Prasath and Subramanian Iyyam Pillai and Sorimuthu Pillai Subramanian},
  journal={European journal of pharmacology},
  year={2014},
  volume={740},
  pages={
          248-54
        }
}
Liver plays a vital role in blood glucose homeostasis. Recent studies have provided considerable evidence that hepatic glucose production (HGP) plays an important role in the development of fasting hyperglycemia in diabetes. From this perspective, diminution of HGP has certainly been considered for the treatment of diabetes. In the present study, we have analyzed the modulatory effects of fisetin, a flavonoid of strawberries, on the expression of key enzymes of carbohydrate metabolism in STZ… CONTINUE READING

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Fisetin induces Sirt1 expression while inhibiting early adipogenesis in 3T3-L1 cells.

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  • 2015
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