First-trimester sonographic diagnosis of holoprosencephaly: value of the "butterfly" sign.

  title={First-trimester sonographic diagnosis of holoprosencephaly: value of the "butterfly" sign.},
  author={W Sepulveda and Victor Dezerega and Cecilia Be},
  journal={Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine},
  volume={23 6},
  pages={761-5; quiz 766-7}
OBJECTIVE To study the value of choroid plexus dysmorphology as a screening tool for the first-trimester sonographic diagnosis of holoprosencephaly in a high-risk population. METHODS A total of 378 consecutive pregnancies undergoing chorionic villus sampling between 11 and 14 weeks' gestation were scanned before the procedure, following the recommendations of the Fetal Medicine Foundation (London, England). A cross-sectional view of the fetal brain, including the visualization of both choroid… CONTINUE READING