First trimester screening of circulating C19MC microRNAs and the evaluation of their potential to predict the onset of preeclampsia and IUGR

Abstract

OBJECTIVES A nested case control study of a longitudinal cohort comparing pregnant women enrolled at 10 to 13 gestational weeks was carried out to evaluate risk assessment for preeclampsia and IUGR based on circulating placental specific C19MC microRNAs in early pregnancy. METHODS The expression of placental specific C19MC microRNAs (miR-516b-5p, miR-517… (More)
DOI: 10.1371/journal.pone.0171756

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