First-trimester screening for trisomy 21 in singleton pregnancies achieved by assisted reproduction.


BACKGROUND The possible effect of assisted reproduction on first-trimester screening for trisomy 21 was examined by fetal nuchal translucency thickness (NT), maternal serum free beta-human chorionic gonadotrophin (HCG) and pregnancy-associated plasma protein-A (PAPP-A). METHODS Parameters were measured at 11-14 weeks in 411 singleton pregnancies achieved… (More)


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