First-trimester screening for trisomy 21 combining biochemistry and ultrasound at individually optimal gestational ages. An interventional study.

Abstract

OBJECTIVE To assess the effectiveness of the Combined Test in the prenatal detection of trisomy 21 in the general pregnant population using a new timing for the screening approach. METHODS First-trimester maternal serum biochemical markers (pregnancy-associated plasma protein-A and free-beta hCG) were determined in maternal serum at 7 to 12 weeks. Fetal… (More)

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Cite this paper

@article{Borrell2004FirsttrimesterSF, title={First-trimester screening for trisomy 21 combining biochemistry and ultrasound at individually optimal gestational ages. An interventional study.}, author={Antoni Borrell and Elena Casals and Albert Fortuny and M Teresa Farre and Anna Gonc{\'e} and Aurora S{\'a}nchez and Anna Soler and Vicençc Cararach and Joan Antoni Vanrell}, journal={Prenatal diagnosis}, year={2004}, volume={24 7}, pages={541-5} }