First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss.

@article{Bramham2011FirsttrimesterLP,
  title={First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss.},
  author={Kate Bramham and Mari R. Thomas and Catherine Nelson-Piercy and Munther A. Khamashta and Beverley J Hunt},
  journal={Blood},
  year={2011},
  volume={117 25},
  pages={6948-51}
}
The objective of this study was to assess pregnancy outcome in women with a history of refractory antiphospholipid antibody-associated pregnancy loss(es) who were treated with early low-dose prednisolone in addition to aspirin and heparin. Eighteen women with antiphospholipid antibodies who had refractory pregnancy loss(es) were given prednisolone (10 mg) from the time of their positive pregnancy test to 14 weeks' gestation. Before low-dose prednisolone was given as treatment, 4 (4%) of 97… CONTINUE READING