First total synthesis of (+/-)-3-aza-11-oxa-1,3,5(10)-trieno steroids.


We set out to describe a new and versatile method for preparing 3-aza-11-oxa-1,3,5(10)-trieno steroids via an intramolecular Diels-Alder cycloaddition of o-quinodimethanes as the key step. The characteristic 1H and 13C NMR spectroscopic features of the synthesized compounds are reported. 


Cite this paper

@article{Oumzil2006FirstTS, title={First total synthesis of (+/-)-3-aza-11-oxa-1,3,5(10)-trieno steroids.}, author={Khalid Oumzil and Malika Ibrahim-Ouali and Maurice Santelli}, journal={Steroids}, year={2006}, volume={71 10}, pages={886-94} }