First synthesis of double headed 1,3,4-oxadiazino[6,5-b]indole acyclo C-nucleosides.

  • Adel Z Nasr
  • Published 2004 in Nucleosides, nucleotides & nucleic acids


Condensation of 1,3-dihydro-2,3-dioxo-2H-indoles (la-c) with galactaric acid bis hydrazide (2) gave the corresponding galactaric acid bis[2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazides] (3a-c). Acetylation of the latter compounds with acetic anhydride in the presence of pyridine at ambient temperature gave the 2,3,4,5-tetra-O-acetylgalactaric acid bis[2… (More)


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